January 2015

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ACT-AD Meeting on Combination Therapy Featured in Expert Review of Neurotherapeutics

In 2014 ACT-AD had two papers outlining the regulatory pathway and rationale for developing combination therapies for Alzheimer’s disease accepted for publication in the peer-reviewed journal, Expert Review of Neurotherapeutics (ERN). These manuscripts detail the proceedings from two consecutive landmark discussions led by ACT-AD in 2012 and 2013 on the action steps necessary for pursuing this promising approach to Alzheimer’s disease treatment. The first paper, “Charting a path toward combination therapy for Alzheimer’s disease,” was published in the January 2015 issue of ERN. The second paper, “Building a roadmap for developing combination therapies for Alzheimer’s disease,” is scheduled for the February 2015 issue of ERN. Note, only the abstract to the journal article is available without a fee.

Volunteers Can Make a Difference for Alzheimer’s Research

As we all know, Alzheimer’s research continues to make huge strides. One of the most important reasons for this success rests in the volunteers who take part in it. The National Institutes of Health has a nationwide database of ongoing clinical trials that are recruiting volunteers. We encourage you to share it with your colleagues. (Read More)

ACT-AD Sterling Silver Sponsor of February NIH Alzheimer’s Research Summit

We are pleased to announce that ACT-AD is a Sterling Silver Sponsor of the National Institute of Health’s Alzheimer’s Disease Research Summit 2015: Path to Treatment and Prevention to be held on February 9-10 in Bethesda, Md. The central goal of the summit is to “continue the development of an integrated multidisciplinary research agenda necessary to address critical knowledge gaps and accelerate the discovery and delivery of effective treatments for Alzheimer’s patients at all stages of disease.” We are excited to be a part of this important event. We encourage you to register if you have not already. Attendance at the summit is free, and the proceedings can also be viewed online. (Read More)

Pat Summitt Alzheimer’s Clinic to Open in Tennessee

The Pat Summitt Foundation and The University of Tennessee Medical Center have announced a partnership to establish an Alzheimer’s disease clinic to be named after the legendary former UT women’s basketball coach. Summitt revealed she had early onset dementia in 2011. Learn more about the clinic and how you can support it. (Read More)

New MRI Technique Detects Early Alzheimer’s

Experts at Northwestern University have developed an MRI approach that detects Alzheimer’s in a living animal in the earliest stages of the disease. This represents a new development in ongoing research to find early signs of Alzheimer’s. The study was published in the journal Nature Nanotechnology. (Read More)

Insulin Spray May Improve Memory in Dementia Patients

A nasal spray delivering a man-made form of insulin may improve memory and other mental capabilities in adults who have mild impairment due to Alzheimer’s dementia. The pilot study at Wake Forest Baptist Medical Center found that those who received the insulin for 21 days showed significant improvements in retaining and processing short-term verbal and visual information. It appeared in the Journal of Alzheimer’s Disease. (Read More)

Issues Related to Heart and Stroke Contribute to Dementia

A growing number of researchers conclude that the most common cause of dementia in older adults appears to be related to a mixture of vascular and Alzheimer’s-related cognitive abnormalities. Experts have also found half of the people who die from Alzheimer’s had evidence of stroke. This appeared in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.  (Read More)